Abel Rodriguez and Kaushik Ghosh
09/13/2009 09:00 AM
Applied Mathematics & Statistics
This paper introduces a flexible class of models for relational data based on a hierarchical extension of the two-parameter Poisson-Dirichlet process. The model is motivated by two different applications: 1) A study of cancer mortality rates in the U.S., where rates for different types of cancer are available for each state, and 2) the analysis of microarray data, where expression levels are available for a large number of genes in a sample of subjects. In both these settings, we are interested in improving estimation by flexibly borrowing information across rows and columns while partitioning the data into homogeneous subpopulations. Our model allows for a novel nested partitioning structure in the data not provided by existing nonparametric methods, in which rows are clustered while simultaneously grouping together columns within each cluster of rows.
